肝移植或肝移植手术是对终期肝病的高度专业化和有效的治疗方法。肝脏捐赠者的数量远低于等待肝移植的患者的数量。目前在美国,有超过14,000名患者等待肝脏移植。由于缺乏捐助器官,每年只有大约7,500种肝脏移植。事实上,每年近2,500人死于等待肝脏移植。

Living donor liver transplantation (LDLT) is one way to address the shortage of donor organs. LDLT allows your health care team to schedule an elective liver transplant operation at a mutually agreed upon time - enabling the donor, the recipient, and their immediate circle of family to plan ahead for absences from work, childcare, and other concerns.

常见问题 - 一般问题

What is a living donor liver transplant?

In a living donor liver transplant (LDLT), a donor provides a portion of his or her liver so that someone - usually a family member or close friend - can receive a needed liver transplant.

Who can receive a portion of a liver from a living donor?

可以考虑有潜在捐赠者的肝移植等候名单中的任何人。我们将审查潜在的收件人的医疗记录,以确保他或她是一个候选人移植的候选人。

Who can be a living liver donor?

Living donors must:

  • 与将收到移植的人关系密切,例如配偶,家庭成员或亲密朋友
  • Be between the ages of 18 and 55
  • Have a blood type that is compatible with the blood type of potential recipient (not necessarily the same blood type)
  • 身体健康:
    • No more than one abdominal surgery
    • 没有心脏病
    • Body mass index (BMI) less than 30
  • 精神上健康

捐赠者和移植行动有什么关系?

On the day of surgery, the donor is usually taken to the operating room first. While the donor is under general anesthesia, the surgeon makes an incision in the upper abdomen. The surgeon removes the gall bladder, and dye is injected into the liver to show the liver’s anatomy in detail. This is called a cholangiogram.

Sometimes, the cholangiogram reveals a problem with the liver that was not found during previous testing. On rare occasions, the transplant will need to be cancelled, and the donor’s incision will be closed.

If the operation proceeds, one of the lobes of the liver will be removed. The donor’s remaining liver will still be able to do its job. The surgery usually lasts between four and six hours.

在捐赠者的胆管造影证实移植过程中可以继续进行后,接收者被带到附近的手术室并为移植准备。肝脏接受者的操作可以持续八到12个小时。

Over the next two months, the part of the liver that was transplanted and the part of the liver that remains in the donor will grow to a normal size. Both livers should be capable of functioning normally.

What are the benefits of living donor transplantation?

  • A liver transplant is the ONLY CURE and life-saving measure for a patient with end stage liver disease (cirrhosis).
  • In our area of the country, 20 to 25 percent of patients will die while waiting for a liver transplant.
  • 现场捐赠者移植将允许在开发更重要的肝相关问题之前进行的操作。这是一个计划的操作,可以降低等待移植患者的应力。

FAQs - For liver transplant recipients

Who can I talk to if I’m not sure a transplant is right for me?

与您的肝病学家谈论移植过程。然后致电宾州卫生米尔顿S.Hershey Medical Cent118金宝搏抽水er的移植团队(800-525-5395or717-531-6092) to set up an appointment. Appointment times are available Mondays from 8 a.m. to 4 p.m. We’ll work with you to schedule further testing.

After you schedule an appointment, you’ll receive a packet in the mail. Please fill in the information requested and return it to our office as soon as possible. If you need to change your appointment time, please call as soon as possible to reschedule.

Someone has offered to donate part of their liver for my transplant. What steps should I take?

Have your potential donor call our office at800-525-5395or717-531-6092, and ask to speak to our living donor coordinator. The coordinator will ask a few questions to see if your potential donor might be suitable. If so, we’ll set up an appointment to see this donor and also ask them to get blood type testing. You and your donor do not have to be the same blood type, but your blood types must be compatible.

How do I get placed on the transplant list?

After your testing is complete, our transplant team will review your records and make a decision about your placement on the list. One of our pre-transplant coordinators will call you to let you know our decision, and you’ll receive a letter in the mail.

What happens after I am placed on the transplant list?

You’ll need to provide blood samples at least every 90 days through your local lab, and you’ll need regular clinic visits. We’ll review your lab values and let you know how often you need to come to the clinic for a visit.

FAQs - For liver transplant donors

I’d like to donate part of my liver for a friend or family member. What steps should I take?

致电宾夕法尼亚州卫生米尔顿S.Hershey Medical118金宝搏抽水 Center的移植办公室:717-531-6092or800-525-5395. Our living donor coordinator will ask some questions about your health to see if you might be a candidate. We may also ask you to have blood tests to confirm your blood type and to make sure you’re healthy enough to be a donor. If tests confirm that you may be a potential donor, we’ll work with you to arrange further testing.

What happens next?

成为一名生活肝脏捐赠者有两个阶段:

阶段1

The first step is to have a checkup by a Donor Advocate Team (DAT). Your safety is our top priority. You are free to talk to anyone on the DAT about any physical, emotional or family concerns related to the donor surgery.

接下来,您将与移植外科医生和肝病学家或肝脏专家相遇。他们会解释手术,以去除肝脏的一部分,手术后预期的内容。他们还将讨论任何可能的副作用或风险。您将收到详细的同意书,以便回家和审查。此表格解释了手术后会收到的操作,风险和护理。

If you decide to move forward with donating part of your liver, you will be scheduled for a more thorough evaluation, including:

  • A physical exam
  • A meeting with a psychiatrist to help you understand how your life might change after the surgery and to talk about any stress you might have now or later
  • A chest X-ray and electrocardiogram (ECG or EKG)
  • A liver ultrasound, using sound waves to create an image of your liver
  • 肺部(肺)功能测试
  • 血液测试
  • A computed tomography (CT or CAT) scan or magnetic resonance imaging (MRI) of the liver

您还需要观看一些教育视频,并与社会工作者和财务顾问会面。

如果DAT确定您可以根据您的测试是一个活生生的捐赠者,您将继续前进到第2阶段。

2

移植手术团队将对您的肝脏进行全面研究,包括血液测试和肝脏活组织检查。如果所有测试确认您可以成为活肝脏捐赠者,我们将安排为您和移植收件人工作的操作时间。

我会在医院和工作中有多长?

您最有可能在移植手术的当天录取医院,并停留五到八天。根据您的恢复和您拥有的工作类型,您可以在六到八周内重返工作岗位。

手术后如何捐赠一部分肝脏会影响我的生活?

肝脏是身体中唯一的器官,可以在一部分被移除后退回。它通常在两个月内返回正常功能和大小。肝脏捐赠不应影响您的肝脏的长期功能。从医院出院后,您需要随访,您需要年度访问,以确保您的肝脏正常运作长期。

作为一个生活捐赠者所涉及的风险是什么?

任何主要手术都有风险。并发症的风险约为30%(7例2例)。与肝脏捐赠相关的死亡风险估计为0.15%(670例1例)。

Most problems related to liver donation are minor and get better on their own. The most common problems are bleeding, infection and pain related to the surgery.

很少,一个问题可能需要另一个手术或medical procedure. The most common problem is a bile leak (5 to 15 percent of cases). Your liver secretes bile to aid in digestion. Most bile leaks get better without the need for surgery. Sometimes, tubes need to be placed endoscopically to aid in healing of this leak. In rare cases, surgery is needed to correct the bile leak.

Another problem that can require treatment is a biliary stricture (narrowing or constriction of the ducts that carry bile from the liver). Some strictures can be fixed by inserting tubes endoscopically and rarely will require surgical repair.

Am I making the right decision in donating part of my liver?

Only you can answer that question. Find out as much as you can about the operation, its risks, and the effect it may have on your life and family before making a decision. You will need to take time off work for evaluation, surgery and recovery. You’ll need to consider how missing work could affect your job, finances, family and life.

The transplant team can answer any questions and provide any information you need to help you decide. The Donor Advocate Team will also make sure you’re fully informed, so you can make the decision that’s right for you.

捐赠一部分肝脏的费用是多少?

您不需要支付您的术前评估,手术,住院住宿或诊所访问,或者在手术后的前三个月内与供体外科有关的任何医疗。收件人的保险将支付您保险未涵盖的所有医疗费用。在从医院回家后,您唯一的直接成本可能是止痛药等药物。您还需要支付与评估和手术相关的运输和非医院住宿费用。

记住,你很快就会回来的l need to take time off work for the evaluation, surgery and recovery, so you should plan your household expenses and finances ahead of time. Be sure to check with your company’s human resources department to learn what your options are under the Family Medical Leave Act and to find out about any short-term disability benefits you may have.